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Comments: This drug may be taken anywhere from 30 minutes to 4 hours before sexual activity.cimetidine, a medicine used to treat ulcers un antibiótico o medicina antifúngica;

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CrCl ≥30 mL/min: No dosage adjustment neededSexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease. Ask your doctor if your heart is healthy enough to handle the extra strain of having sex.